Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection
نویسندگان
چکیده
Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mixed infection. Diagnostic techniques that identify mixed tubercle bacilli populations are needed to curb the spread of multidrug resistance.
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عنوان ژورنال:
دوره 19 شماره
صفحات -
تاریخ انتشار 2013